Episodes
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S06 E01
Hilary Swank, Sean Lennon, Charlotte Kemp Muhl
September 8, 2020
• 40m
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S06 E02
Gabrielle Union, Nick Cave
September 9, 2020
• 40m
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S06 E03
Usher, Joan Jett
September 10, 2020
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S06 E04
Dr. Phil McGraw, Kelsea Ballerini
September 14, 2020
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S06 E05
Rainn Wilson, Anthony Ramos
September 15, 2020
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S06 E06
John David Washington, Michael McIntyre, Glass Animals
September 16, 2020
James welcomes actor John David Washington, comedian Michael McIntyre, and a musical performance by Glass Animals.
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S06 E07
Neil Patrick Harris, Ziggy Marley, Ben Harper
September 17, 2020
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S06 E08
Alicia Keys
September 21, 2020
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S06 E09
Ken Jeong, Alicia Keys, Khalid
September 22, 2020
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S06 E10
Sharon Stone, Alicia Keys
September 23, 2020
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S06 E11
Jason Schwartzman, Alicia Keys
September 24, 2020
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S06 E12
Jeff Daniels, Summer Walker
September 28, 2020
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S06 E13
Andrew Rannells, Brittany Howard
September 29, 2020
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S06 E14
Hillary Clinton
September 30, 2020
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S06 E15
Tyra Banks, Evan Rachel Wood
October 1, 2020
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S06 E16
Seth MacFarlane, Jaded Hearts Club
October 5, 2020
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S06 E17
Whoopi Goldberg, Bishop Briggs
October 6, 2020
Whoopi Goldberg and Bishop Briggs are spotlighted.
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S06 E18
Gloria Steinem, Sally Hawkins, Craig Roberts, Conan Gray
October 7, 2020
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S06 E19
Armie Hammer, Surfaces
October 8, 2020
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S06 E20
Bill Gates, The Head and the Heart
October 21, 2020
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S06 E21
Josh Gad, The Score, AWOLNATION
October 22, 2020
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S06 E22
Jeremy Strong, SuperM
October 23, 2020
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S06 E23
Aaron Sorkin, The Shins
October 26, 2020
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S06 E24
Billy Porter, David Byrne, Kane Brown
October 27, 2020
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S06 E25
Chelsea Handler, CL
October 28, 2020
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S06 E26
Vin Diesel, Jack Peñate
October 29, 2020
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S06 E27
Pete Buttigieg, Travis
November 2, 2020
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S06 E28
Henry Winkler, The Kills
November 4, 2020
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S06 E29
Tig Notaro, Christine and the Queens
November 5, 2020
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S06 E30
Dr. Michael Eric Dyson, Henry Golding, Ella Mai
November 6, 2020
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S06 E31
David Oyelowo, Sam Smith
November 9, 2020
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S06 E32
Thomas Middleditch, Black Pumas
November 10, 2020
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S06 E33
Max Greenfield, Ashe, Niall Horan
November 11, 2020
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S06 E34
Cory Booker, Jack Harlow
November 12, 2020
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S06 E35
Will Arnett, Maria Bakalova
November 16, 2020
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S06 E36
Melissa McCarthy, Bobby Cannavale, FITZ
November 17, 2020
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S06 E37
Alison Brie, Yuval Noah Harari
November 18, 2020
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S06 E38
Marc Maron, Royal Blood
November 19, 2020
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S06 E39
Michael J. Fox, BTS
November 23, 2020
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S06 E40
Goldie Hawn, Kurt Russell, BTS
November 24, 2020
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S06 E41
Chris Rock, Rauw Alejandro, J Balvin
November 25, 2020
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S06 E42
John Lithgow, Gary Barlow
December 1, 2020
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S06 E43
Riz Ahmed, Bad Bunny
December 2, 2020
• 40m
Actor Riz Ahmed (Sound of Metal); Bad Bunny performs.
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S06 E44
Bryan Cranston, Rufus Wainwright
December 3, 2020
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S06 E45
Kevin Bacon, Jamie Oliver
December 4, 2020
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S06 E46
Matthew McConaughey, Shawn Mendes
December 7, 2020
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S06 E47
Meryl Streep, Billy Eichner
December 8, 2020
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S06 E48
Jamie Dornan, Dr. Michael Eric Dyson
December 9, 2020
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S06 E49
Andrew Rannells, Megan Thee Stallion
December 10, 2020
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S06 E50
Kyle Chandler, Meghan Trainor
December 14, 2020
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S06 E51
Keegan-Michael Key, Roddy Ricch
December 15, 2020
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S06 E52
Nicole Kidman, Kerry Washington, Phoebe Bridgers
December 16, 2020
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S06 E53
Gal Gadot, Smith & Burrows
December 17, 2020
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S06 E54
Rosario Dawson, Ingrid Andress
January 4, 2021
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S06 E55
James Marsden, Tim Minchin
January 5, 2021
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S06 E56
Jim Gaffigan, Seventeen
January 6, 2021
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S06 E57
Michael Sheen, Jo Ellen Pellman
January 7, 2021
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S06 E58
Rob Lowe, Zoe Wees
January 11, 2021
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S06 E59
Liam Neeson, Annaleigh Ashford, Pillow Queens
January 12, 2021
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S06 E60
Paul Bettany, Lennie James
January 13, 2021
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S06 E61
Michael Moore, Andie MacDowell, Why Don't We
January 14, 2021
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S06 E62
Anthony Mackie, Machine Gun Kelly
January 19, 2021
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S06 E63
Dakota Johnson, AJR
January 20, 2021
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S06 E64
Regina King, Amanda Gorman
January 21, 2021
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S06 E65
Rob Gronkowski, Joe Montana, Stephen Curry
January 24, 2021
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S06 E66
Halsey, Penn & Teller
January 25, 2021
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S06 E67
Jared Leto, Jacob Collier
January 26, 2021
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S06 E68
Adam Devine, BLACKPINK
January 27, 2021
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S06 E69
Carey Mulligan, Jhene Aiko
January 28, 2021
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S06 E70
Viggo Mortensen, Quinn XCII, Chelsea Cutler
February 1, 2021
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S06 E71
Naomi Watts, FINNEAS
February 2, 2021
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S06 E72
Kal Penn, Josh Groban
February 3, 2021
• 40m
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S06 E73
Dan Stevens, Michael Kiwanuka
February 4, 2021
• 40m
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S06 E74
Salma Hayek, Owen Wilson, The Weeknd
February 8, 2021
• 40m
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S06 E75
Rob Gronkowski, Elle Fanning, Sabrina Carpenter
February 9, 2021
• 40m
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S06 E76
Noah Centineo, Madison Cunningham
February 10, 2021
• 40m
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S06 E77
Mila Kunis, Robin Thicke
February 11, 2021
• 40m
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S06 E78
Kristen Wiig, Annie Mumolo, Masego and Don Toliver
February 22, 2021
• 40m
Kristen Wiig; Annie Mumolo; musical performance by Masego feat. Don Toliver.
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S06 E79
Drew Barrymore, Storm Reid
February 23, 2021
• 40m
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S06 E80
Stanley Tucci, Pentatonix
February 24, 2021
• 40m
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S06 E81
Jodie Foster, Prince Harry, Holly Humberstone
February 25, 2021
• 40m
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S06 E82
Jamie Dornan, Kelly Marie Tran
March 1, 2021
• 40m
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S06 E83
Tom Brady, Stacey Abrams, JP Saxe, Maren Morris
March 2, 2021
• 40m
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S06 E84
Ben Schwartz, Foo Fighters
March 3, 2021
• 40m
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S06 E85
Daisy Ridley, Caroline Polachek
March 4, 2021
• 40m
Daisy Ridley; musical performance by Caroline Polachek.
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S06 E86
Andra Day, SG Lewis, Nile Rodgers
March 8, 2021
• 40m
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S06 E87
Tracy Morgan, Kings of Leon
March 9, 2021
• 40m
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S06 E88
Trevor Noah, Grouplove
March 10, 2021
• 40m
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S06 E89
Eddie Murphy, Tiana Major9
March 11, 2021
• 40m
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S06 E90
Venus Williams, Picture This
March 15, 2021
• 40m
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S06 E91
Chuck Schumer, Sam Smith
March 16, 2021
• 40m
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S06 E92
Allison Janney, Inhaler
March 17, 2021
• 40m
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S06 E93
Benedict Cumberbatch, Justin Bieber
March 18, 2021
• 40m
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S06 E94
David Tennant, Joy Downer
March 22, 2021
• 40m
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S06 E95
Bear Grylls, Middle Kids
March 23, 2021
• 40m
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S06 E96
Minnie Driver, Benny Blanco, Gracie Abrams
March 24, 2021
• 40m
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S06 E97
Chrissy Teigen, NEEDTOBREATHE
March 25, 2021
• 40m
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S06 E98
Bob Odenkirk, The Fratellis
April 5, 2021
• 40m
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S06 E99
Neil deGrasse Tyson, Arlo Parks
April 6, 2021
• 40m
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S06 E100
Kenan Thompson, Julien Baker
April 7, 2021
• 40m
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S06 E101
Jeffrey Dean Morgan, London Grammar
April 8, 2021
• 40m
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S06 E102
Rainn Wilson, Tom Odell
April 12, 2021
• 40m
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S06 E103
Vanessa Kirby, Darren Criss
April 13, 2021
• 40m
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S06 E104
Keith Urban, Jon Batiste
April 14, 2021
• 40m
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S06 E105
Forest Whitaker, Kane Brown
April 15, 2021
• 40m
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S06 E106
Ron Funches, Karol G
April 19, 2021
• 40m
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S06 E107
Angela Bassett, KSI, Yungblud, Polo G
April 20, 2021
• 40m
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S06 E108
Cher, Jackson Wang
April 21, 2021
• 40m
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S06 E109
Dominic Cooper, Static & Ben El, Black Eyed Peas
April 22, 2021
• 40m
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S06 E110
Pete Buttigieg, Jordan McGraw
April 26, 2021
• 40m
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S06 E111
Zion Williamson, Years & Years
April 27, 2021
• 40m
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S06 E112
Jason Schwartzman, Gabby Barrett
April 28, 2021
• 40m
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S06 E113
Brian Tyree Henry, Tom Grennan
April 29, 2021
• 40m
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S06 E114
Tiffany Haddish, Dominic Fike
May 3, 2021
• 40m
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S06 E115
Ellen DeGeneres, Wolf Alice
May 4, 2021
• 40m
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S06 E116
Billy Porter, Brett Gelman
May 5, 2021
• 40m
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S06 E117
Max Greenfield, Alec Benjamin
May 6, 2021
• 40m
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S06 E118
David Oyelowo, Maisie Peters
May 10, 2021
• 40m
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S06 E119
Martin Freeman, Rag'n'Bone Man
May 11, 2021
• 40m
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S06 E120
Sharon Stone, Matthew Rhys
May 12, 2021
• 40m
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S06 E121
Ben Platt
May 13, 2021
• 40m
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S06 E122
Barack Obama, Kelly Rowland
May 17, 2021
• 40m
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S06 E123
Regina Hall, Moby
May 18, 2021
• 40m
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S06 E124
Eric Bana, Pete Holmes
May 19, 2021
• 40m
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S06 E125
Hank Azaria, Sara Bareilles
May 20, 2021
• 40m
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S06 E126
Don Cheadle, Rafe Spall
May 24, 2021
• 40m
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S06 E127
Andrew Rannells, All Time Low
May 25, 2021
• 40m
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S06 E128
Jonas Brothers, Leif Vollebekk
May 26, 2021
• 40m
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S06 E129
Emily Blunt, Elle King
May 27, 2021
• 40m
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S06 E130
Julianne Moore, Rufus Wainwright
June 7, 2021
• 40m
James welcomes actress Julianne Moore and a musical performance by Rufus Wainwright.
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S06 E131
Chelsea Handler, The Wallflowers
June 8, 2021
• 40m
James welcomes actress Chelsea Handler and a musical performance by The Wallflowers.
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S06 E132
Lisa Kudrow, Clea Duvall, Rostam
June 9, 2021
• 40m
James welcomes actress Lisa Kudrow, actress Clea DuVall, and a musical performance by Rostam.
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S06 E133
Desus & Mero, Mother Mother
June 10, 2021
• 40m
James welcomes the podcast hosts of Desus & Mero and a musical performance by Mother Mother.
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S06 E134
Hugh Grant, Mike Colter, Tomorrow X Together
June 14, 2021
• 40m
James welcomes actor Hugh Grant, actor Mike Colter, and a musical performance by Tomorrow X Together.
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S06 E135
Gavin Newsom, Migos
June 15, 2021
• 40m
James welcomes governor Gavin Newsom and rap group Migos.
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S06 E136
Margot Robbie, Rose Byrne, Polo G
June 16, 2021
• 40m
James welcomes actress Margot Robbie, actress Rose Byrne, and a musical performance by Polo G.
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S06 E137
Will Arnett, Lord Huron
June 17, 2021
• 40m
James welcomes actor Will Arnett and a musical performance by Lord Huron.
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S06 E138
Helen Hunt, Black Pumas
June 21, 2021
• 40m
James welcomes actress Helen Hunt and a musical performance by Black Pumas.
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S06 E139
Elizabeth Olsen, Edgar Wright
June 22, 2021
• 40m
James welcomes actress Elizabeth Olsen and film director Edgar Wright.
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S06 E140
Josh Gad, Chloe Moriondo
June 23, 2021
• 40m
James welcomes actor Josh Gad and a musical performance by Chloe Moriondo.
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S06 E141
Liam Neeson, Anthony Ramos
June 24, 2021
• 40m
James welcomes actor Liam Neeson and a musical performance by Anthony Ramos.
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S06 E142
Ed Sheeran
June 28, 2021
• 40m
James welcomes a talk and a musical performance by Ed Sheeran.
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S06 E143
Steve Buscemi, Ed Sheeran
June 29, 2021
• 40m
James welcomes actor Steve Buscemi and a musical performance by Ed Sheeran.
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S06 E144
Heidi Klum, Ed Sheeran
June 30, 2021
• 40m
James welcomes television host Heidi Klum and a musical performance by Ed Sheeran.
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S06 E145
Chris Pratt, Ed Sheeran
July 1, 2021
• 40m
James welcomes actor Chris Pratt and a musical performance by Ed Sheeran.
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S06 E146
Jason Momoa, Lorde
August 23, 2021
• 40m
James welcomes actor Jason Momoa and a musical performance by Lorde.
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S06 E147
Lorde
August 24, 2021
• 40m
James welcomes a talk and musical performance by Lorde.
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S06 E148
Bradley Whitford, Lorde
August 25, 2021
• 40m
James welcomes actor Bradley Whitford and a musical performance by Lorde.
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S06 E149
Terry Crews, Lorde
August 26, 2021
• 40m
James welcomes actor Terry Crews and a musical performance by Lorde.
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S06 E150
Camila Cabello, Rufus Du Sol
August 30, 2021
• 40m
James welcomes singer Camila Cabello, and a musical performance by Rufus Du Sol.
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S06 E151
Lil Rel Howery, Billie Piper
August 31, 2021
• 40m
James welcomes actor Lil Rel Howery and actress Billie Piper.
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S06 E152
Clive Owen, James Arthur
September 1, 2021
• 40m
James welcomes actor Clive Owen, and a musical performance by James Arthur.
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S06 E153
David Duchovny, The Killers
September 2, 2021
• 40m
James welcomes actor David Duchovny and a musical performance by The Killers.